Epithelial-to-mesenchymal transition (EMT) in cancer cells facilitates tumor progression by promoting invasion and metastasis. Snail is a transcriptional factor that induces EMT. while P-glycoprotein (P-gp) is an efflux transporter involved in anticancer drug resistance. and P-gp efflux activity is stimulated in Snail-overexpressing lung cancer cells with EMT characteristics. https://jalyttlers.shop/product-category/bedlinen/
Entinostat reverses P-glycoprotein activation in snail-overexpressing adenocarcinoma HCC827 cells.
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